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Monday, May 18, 2020 | History

4 edition of Molecular mechanisms of antibiotic action on protein biosynthesis and membranes found in the catalog.

Molecular mechanisms of antibiotic action on protein biosynthesis and membranes

Molecular mechanisms of antibiotic action on protein biosynthesis and membranes

Proceedings of a symposium held at the University of Granada (Spain) June 1st-4th, 1971

  • 391 Want to read
  • 13 Currently reading

Published by Elsevier Publ. Co .
Written in English


The Physical Object
Number of Pages804
ID Numbers
Open LibraryOL7529931M
ISBN 100444410422
ISBN 109780444410429

  SUMMARY The increased use of antibacterial and antifungal agents in recent years has resulted in the development of resistance to these drugs. The significant clinical implication of resistance has led to heightened interest in the study of antimicrobial resistance from different angles. Areas addressed include mechanisms underlying this resistance, improved methods to detect resistance Cited by: Antibiotics are chemotherapeutic agents, which have been a very powerful tool in the clinical management of bacterial diseases since the s. However, benefits offered by these magic bullets have been substantially lost in subsequent days following the widespread emergence and dissemination of antibiotic-resistant strains. While it is obvious that excessive and imprudent use of antibiotics Cited by:

  Natural antimicrobial peptides from bacteria: characteristics and potential applications to fight against antibiotic resistance. M. Hassan. Mechanisms of action of bacteriocins. Rationale design of peptides relies on detailed understanding of the peptides' structure as well as the molecular mechanisms underlying modification, processing Cited by: UB Introductory Biology-III (Cell Biology, Immunology and Neurobiology) Eukaryotic cells and organelles, cell membranes and cell function. Introduction to animal viruses with examples, life cycle and host-virus interactions. Introduction to the immune system – the players and mechanisms, innate immunity, adaptive responses, BFile Size: KB.

Protein synthesis inhibitors usually act at the ribosome level, taking advantage of the major differences between prokaryotic and eukaryotic ribosome structures. A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria or any other membrane-bound tion: Oral. Various rhizosphere bacteria are potential (micro)biological pesticides which are able to protect plants against diseases and improve plant yield. Knowledge of the molecular mechanisms that govern these beneficial plant–microbe interactions enables optimization, enhancement and identification of potential synergistic effects in plant by:


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Molecular mechanisms of antibiotic action on protein biosynthesis and membranes Download PDF EPUB FB2

Symposium on Molecular Mechanisms of Antibiotic Action on Protein Biosynthesis and Membranes ( Granada, Spain). Molecular mechanisms of antibiotic action on protein biosynthesis and membranes. Amsterdam, New York, Elsevier Publ. Co., (OCoLC) Material Type: Conference publication: Document Type: Book: All Authors / Contributors.

Book reviewed in this article: Molecular Mechanisms of Antibiotic Action on Protein Biosynthesis and Membranes. Proceedings of a Symposium at the University of Granada.

Munoz, F. Garcia‐Ferrandiz, and D. Vazquez, editors. Modern Inhalation Anesthetics. Maynard B. Chenoweth, editor. Steroids and Brain Edema. Reulen and K. Schürmann. Further details will be found in the article “Molecular Basis for the Action of Macrocyclic Antibiotics on Membranes”, by G. Eisenman, G.

Szabo, S.G.A. McLaughlin and S.M. Ciani, in Symposium on Molecular Mechanisms of Antibiotic Action on Protein Biosynthesis and Membranes, D.

Author: G. Eisenman, G. Szabo, S. McLaughlin, S. Ciani. Author(s): Muñoz,Emilio; García Ferrándiz,Francisco; Vázquez,David; Symposium on Molecular Mechanisms of Antibiotic Action on Protein Biosynthesis and Membranes,( University of Granada) Title(s): Molecular mechanisms of antibiotic action on protein symposium held at the University of Granada (Spain) June 1st-4th, We also cover virulence factors, mechanisms of antibiotic resistance, insights from whole-genome sequencing and immune responses.

The potential therapeutic effects of propionibacteria when used as adjuvants/vaccines are also considered, along with molecular-based approaches for differentiation and characterization of propionibacteria associated.

MOLECULAR MECHANISMS OF THE BIOGENESIS OF EXOPROTEINS IN BACTERIA. ROLE OF MEMBRANES IN ENVIRONMENTAL REGULATION OF METABOLISM M.A. Nesmeyanova Institute of BioeherrrCstry and Physiology of Microorganisms, USSR Academy of Sciences, Pushchino, Moscow region,USSR INTRODUCTION The two great problems indicated by the title naturally cannot Author: M.A.

Nesmeyanova. Antibiotic mechanisms of action and the opposing mechanisms of resistance are intimately associated, but comprehension of the biochemical and molecular functions of such drugs is not a simple.

Dear Colleagues, The emergence of bacterial resistance to available antibiotics is a threat to public health and health systems worldwide. This fast increase and spread of resistance to multiple antibiotics among bacteria has not been accompanied with the introduction in the market of novel antibiotics, leading organizations like the World Health Organization to announce a global crisis of.

Describe the mechanisms of action associated with drugs that inhibit cell wall biosynthesis, protein synthesis, membrane function, nucleic acid synthesis, and metabolic pathways An important quality for an antimicrobial drug is selective toxicity, meaning that it selectively kills or inhibits the growth of microbial targets while causing.

The Process of Antibiotic Discovery The Economics of Antibiotic Discovery Mechanisms of Antibiotic Action Targets of Antibiotic Action Cell Wall Synthesis Inhibitors Protein Synthesis Inhibitors Antibiotics That Target DNA and RNA Synthesis Inhibitors of Tetrahydrofolate Biosynthesis The Newest.

The complement regulatory protein, CD46 (or membrane cofactor receptor), is a human-specific, transmembrane protein that is expressed by all nucleated cells. In some cells, CD46 has been demonstrated to serve as a receptor for gonococcal pilus (, ).Cited by: Because of the wealth of information within the covers of this important book, all those involved in research into drug action and development, whether in the pharmaceutical industry or academia, will find Biochemistry and Molecular Biology of Antimicrobial Drug Action invaluable.

Presented in part at the Symposium on Molecular Mechanisms of Antibiotic Action Protein Biosynthesis and Membranes, Granada, Spain, June, Supported by NSF Grant GB and USPHS Grants GM and NS Cited by: Antibiotics: Classification and mechanisms of action with emphasis on molecular perspectives Article (PDF Available) January w Reads How we measure 'reads'.

Bacterial infections caused by antibiotic-resistant isolates have become a major health problem in recent years, since they are very difficult to treat, leading to an increase in morbidity and mortality. Fosfomycin is a broad-spectrum bactericidal antibiotic that inhibits cell wall biosynthesis in both Gram-negative and Gram-positive bacteria.

This antibiotic has a unique mechanism of action Cited by: A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance. Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources.

Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is Cited by:   A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance.

Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources.

Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is Brand: ASM Press.

The new antibiotic may then be compared against standard antibiotics used against such bacterial infections, with both antibiotic-sensitive and antibiotic-resistant strains of pathogens.

Bacteria and fungi that make antibiotics need self-protection or autoimmunity mechanisms to protect themselves from the lethal chemical weapons they are by: Written by specialists in the field, this book provides a comprehensive overview of the structural and molecular biology of cellular processes that occur at or near bacterial membranes.

The book presents and discusses recent progress on the function and involvement of membranes in bacterial physiology, enabling a greater understanding of the. More Less Abstract: Antibiotics are organic molecules usually of low molecular weight.

Antibiotics: Challenges, Mechanisms, Opportunities details the contemporary challenges for discovery, optimization, and advancement of new antibiotics. It focuses on discovery not preclinical or clinical development.

Given that the few classes of clinically significant antibiotics are all small molecules, this book focuses on the molecular structures and characteristics of both natural and. Describe the mechanisms of action associated with drugs that inhibit cell wall biosynthesis, protein synthesis, membrane function, nucleic acid synthesis, and metabolic pathway.

An important quality for an antimicrobial drug is selective toxicity, meaning that it selectively kills or inhibits the growth of microbial targets while causing.-essentially same molecular mechanism The simultaneous expression of various antibiotic resistance mechanisms, each specific for a drug or class of drugs.

regulon. master switch which achieves co-expression of -also inhibit protein biosynthesis, specifically by interaction with.